Vale Health Injection Clinic

Botox (Botulinum Toxin) for the Treatment of Migraines

Botox – An Alternative Treatment to End Pain



Chronic migraine


None Required


Procedure Time
30 Minutes


Back To Work

Improved quality of life

non-invasive approach 30 minute procedure

Fast recovery

An effective pain relief option

Botox for Migraine Overview

Botox, derived from the bacteria Clostridium botulinum, is a nerve toxin renowned for its muscle-paralysing properties. Initially recognised for its effectiveness in cosmetic procedures, it was later discovered to benefit individuals suffering from migraines, resulting in reduced headache frequency.


The mechanism behind its efficacy is believed to involve the blocking of neurotransmitters responsible for transmitting pain signals within the brain. This versatile toxin is also utilised in the treatment of various health conditions, including cerebral palsy, bladder pain, lower back pain, neuropathic pain, and stroke.

What are stem cells, and how DO THEY WORK
BMAC (Bone Marrow Aspirate Concentrate) harnesses the body’s innate healing capabilities through a minimally invasive procedure. Derived from bone marrow, which houses two main types – red and yellow – BMAC primarily utilizes the regenerative potential of mesenchymal stem cells (MSCs) found in yellow marrow. These MSCs are versatile, capable of differentiating into various cell types crucial for tissue repair, such as chondrocytes, osteoblasts, tenocytes, fibroblasts, and connective tissues.
Unlike other sources of stem cells like adipose tissue, BMAC-derived MSCs possess a notable capacity for bone and cartilage formation. Moreover, they exhibit tissue-specific differentiation abilities, although this can vary among donors.
When applied to an injury site, BMAC initiates a cascade of healing responses. BMSCs secrete specialized substances tailored to the injured tissue, which modulate inflammation, stimulate self-repair, and enhance regeneration. This process not only alleviates immediate pain but also offers long-term relief by promoting anti-inflammatory and anti-bacterial activities.
What is nSTRIDE® APS?

Introducing nSTRIDE® APS, a breakthrough treatment for knee joint inflammation. This innovative therapy involves a precisely formulated injection of concentrated beneficial proteins derived from your own blood directly into the affected knee joint. By harnessing the body’s natural healing mechanisms, nSTRIDE® APS aims to not only alleviate pain but also restore equilibrium to your inflamed knee.

Clinical research has showcased the efficacy of a single injection, indicating that its benefits may persist for 24-36 months. Additionally, more recent data suggests that certain individuals may experience pain relief for as long as five years following the treatment. cartilage, bone, tendons, and ligaments.

If you’re experiencing early or moderate-stage osteoarthritis and have found no relief with other conservative treatments, nSTRIDE® APS could be a suitable option for you. Please give us a call and we can book you in for initial assessment to ascertain the most suitable and beneficial treatment.

Following nSTRIDE® APS treatment, patients may encounter localised pain and swelling at the injection site, typically resolving within 24-48 hours. There are no enduring side effects associated with the procedure; however, it’s advisable to have someone accompany you on the day of treatment.


Within 4-5 days post-treatment, a slight reduction in swelling, stiffness, and pain can be anticipated. While some individuals may experience diminished knee discomfort within 1-2 weeks, most patients typically notice pain relief between 4-8 weeks following the procedure. Significant pain reduction may take up to 12 weeks to manifest.

For optimal recovery, it’s recommended to limit activity levels for 14 days post-treatment.


At London Bridge Regeneration clinic we provide various payment options meaning you can spread the cost and enjoy a confident outlook at a price you can afford this can also include interest free options.
Please book a complimentary initial consultation to discuss, your tailored and best options your but typically prices start as shown below
Procedure Specialists


Botox injections for Migraines


£500 per visit

Long-Lasting Relief: Botox injections for migraines typically provide relief that lasts for several months

Non-Invasive Treatment Option: Botox injections offer a non-invasive approach to migraine management, making them suitable for individuals who prefer to avoid more invasive procedures or who have not responded well to other treatments. Additionally, Botox injections are generally well-tolerated with minimal side effects.


Research is ongoing to find out the mechanism behind the effectiveness of botulinum toxin-based medications in relieving headache associated pain. Evidence indicates that these drugs disrupt the pathway through which pain signals travel between the brain (central nervous system) and the nerves extending from the spinal cord.

During a migraine episode, the body releases neurotransmitters and pain-associated chemicals. Botulinum toxin disrupts the transmission of these substances, particularly at the junctions where nerves and muscles connect. It is believed that when injected into the muscles surrounding the face, head, and neck, the toxin is absorbed by the nerves, interfering with the transmission of pain signals.

After the procedure, we highly recommend that you remain in the clinic for at least 30 minutes for observation and to ensure there are no immediate complications. Following this observation period, we typically advise refraining from engaging in strenuous physical activities for several days to allow your body to recover optimally. It’s essential to prioritize hydration by drinking plenty of water to help flush out any toxins and aid in the healing process. If you experience any discomfort or pain, Paracetamol can be safely used for pain management as needed.

While you are capable of returning home independently, some individuals may opt to have someone accompany them, particularly during their initial visit. While it’s advisable to take the remainder of the day off, additional time off following the procedure is not mandatory.

To prevent infection and ensure complete absorption of the injected drug, it is recommended to avoid the following activities during the initial 24 hours:

  • Intense exercise (e.g., gym workouts, jogging)
  • Hair washing (consider washing your hair the day before your appointment)
  • Cleansing the skin in areas where injections were administered
  • Massages and exposure to extreme heat, such as spas

You may experience bruising or tenderness in the injected areas for a few days, and it’s possible that your migraine symptoms may temporarily worsen or you may experience a migraine attack in the days following the treatment. During this period, you can use your usual acute treatment (e.g., painkillers, triptans) as needed. The benefits of the treatment typically manifest within one to two weeks after the injections.

Since Botox is administered in two separate treatments, spaced three months apart, the full effect may only be experienced after the second set of injections. Therefore, lack of immediate effect after the first treatment does not necessarily indicate that the treatment is ineffective. Remember to maintain a daily headache diary and bring it to your next clinic appointment.


Step 1. Free Intial consultation

London Bridge Regenerative clinic gives every patient a free consultation with one of our injecting practitioners.

There is no obligation to proceed to treatment. The consultation is an opportunity to discuss your issue in detail and the benefits and risks of the procedure.

According to the last NICE publication, over 6 MILLION people in the UK suffer from migraines and headaches each year. 


We will allow time to find out more about the procedure, understand the advantages and risks with the procedure, and to give time for you to ask questions We may need to refer you for an MRI

We  will then take your medical history, examine which may include diagnostic ultrasound then proceed with the guided injection.


You’ll be given individual pre-injection advice to reduce your chance of bleeding or infection and support your recovery and aid healing

It’s important to let your practitioner know if you’re on any prescription or over-the-counter medications. You may be asked to stop taking aspirin or anti-inflammatory tablets, which can increase the risk of bruising. It’s also important to stop smoking cigarettes and e-cigarettes before and after the procedure because they can disrupt the healing process.

Local anesthetic is not needed for this procedure and the procedure is tolerated very well. 


Following the procedure, most individuals can return home and resume their normal activities. Our clinical team will be available to offer water and provide guidance on post-injection care.

For the next twenty-four hours, it’s advisable to refrain from strenuous activities and alcohol consumption. Don’t be alarmed if you don’t notice immediate effects; it typically takes around five days for the injection to take effect, with the full results becoming evident over the course of several weeks.

A follow-up appointment or phone consultation will be scheduled for four weeks after the procedure to review the progress. 



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