Vale Health Injection Clinic

Arthrosamid injection

Restoring your mobility & function.



Knee Osteoarthritis


 Local anesthetic


1 hour


A couple days of reduced activity 

Repair of the injured tissue

Accelerated healing

Restoration of the damaged tissue.

Eliminate the need for more aggressive treatments, such as surgery

long-lasting pain relief for knee osteoarthritis through a single injection while ensuring safety.

Arthrosamid injection: an innovative new advanced treatment for knee arthritis!

Knee osteoarthritis is a prevalent condition seen in clinics. Typically, treatment for knee osteoarthritis begins with conservative approaches and the use of anti-inflammatory drugs. However, when conventional methods prove ineffective, injection therapy emerges as a crucial component in management. Arthrosamid presents a promising new treatment avenue for knee arthritis. Book a free initial assessment today at London Bridge Regenerative Clinic.

London Bridge Regenerative Clinic

Arthrosamid presents an encouraging new therapeutic choice for knee arthritis, with its roots tracing back to Denmark and its availability in the UK for a few years now, research results are looking promising for the injections long term efficacy.


Arthrosamid® stands out as a new long lasting approach to treating knee osteoarthritis, providing patients with a compelling long ter alternative to existing therapies such as steroids. Utilizing cutting-edge non-biodegradable hydrogel technology, Arthrosamid® comprises 2.5% cross-linked polyacrylamide and 97.5% water. Upon injection into the knee, Arthrosamid® effectively cushions the joint, alleviating pain and offering safe, long-lasting relief, all achieved with just a single injection.

What Evidence Supports the Use of Arthrosamid Injections in Knee Arthritis?

In recent years, several small-scale studies have examined the efficacy and safety of Arthrosamid for treating knee arthritis. These studies have shown notable improvements in knee pain and swelling post-injection, along with enhancements in scores assessing the severity of knee arthritis and its impact on quality of life. More recently, larger and more robust studies have been conducted to evaluate the effects of Arthrosamid. For instance, a multi-center, double-blinded, randomized controlled trial compared the effects of Hydrogel injections to Hyaluronic acid, revealing positive outcomes in both patient groups for up to one year . Bliddal, H., et al. (2022). One-year performance of polyacrylamide hydrogel vs. hyaluronic acid in age, BMI, and Kellgren-Lawrence subgroups: A subgroup analysis of a randomised study. Osteoarthritis and Cartilage Vol.30, Supplement 1, S373-S374.

The most recent data on Arthrosamid injection suggests its effectiveness persists in many patients even three years after the procedure. This prospective study, involving patients with an average age of approximately 70 years, found that the hydrogel forms a stable, long-lasting layer covering the joint surface . 

Arthrosamid has demonstrated both efficacy and safety in relieving symptomatic knee osteoarthritis, making it a generally favorable treatment option for numerous patients. Nonetheless, it’s recommended to consult with one of our injection practitioners who can thoroughly explain the risks and benefits of the procedure, as well as explore alternative therapies that may be beneficial.


Administering the Arthrosamid hydrogel involves directly injecting it into the knee joint under ultrasound guidance, a crucial step for ensuring maximum precision and accuracy in delivery. Research indicates that unguided knee injections have an accuracy rate of approximately 80%.

  • Existing knee replacement or prosthesis.
  • History of knee keyhole surgery (arthroscopy) within the past 6 months.
  • Certain conditions affecting the joints, such as haemophilia, autoimmune diseases, or inflammatory arthritis.
  • Recent hyaluronic acid injection into the knee; it’s advised to wait until the previous injection is absorbed, with the duration varying according to the specific hyaluronic acid preparation used.
  • Certain medications and blood disorders. This will be fully discussed during your initial consultation to ascertain the suitability of the treatment and answer any questions you may have.

Arthrosamid is administered with ultrasound guidance to enhance the precision and safety of the injection process. Without ultrasound guidance, the accuracy of knee injections is only around 80%, as shown by studies. Therefore, utilizing ultrasound ensures that Arthrosamid is injected precisely into the knee joint, maximizing its effectiveness and safety for the patient.

The duration of Arthrosamid’s effect is promising, with recent studies showing that its benefits were maintained for up to 3 years of follow-up. Contura, the manufacturer of Arthrosamid, is actively monitoring the long-term response to this hydrogel treatment. Since the Arthrosamid hydrogel cannot be degraded by the body, it offers the potential for long-term pain relief, providing patients with sustained benefits over time.

Patients typically begin to notice pain relief within a few weeks after receiving the injection. It is common to experience temporary discomfort in the knee for the first few days after the procedure. The full benefit of the injection may take around 4 weeks to become apparent, and it could take up to 12 weeks to experience the maximum relief from the procedure.

At London Bridge Regeneration clinic we provide various payment options meaning you can spread the cost and enjoy a confident outlook at a price you can afford this can also include interest free options.
Please book a complimentary initial consultation to discuss, your tailored and best options your but typically prices start as shown below
Procedure Specialists

Practitioner fee


Gary Edwards


Arthrosamid Injection

How Does Arthrosamid Work to Treat Knee Pain?

The knee joint comprises a thin membrane known as the synovium, which houses small synovial cells responsible for producing lubricant fluid, allowing the joints to glide and acting as a shock absorber. In cases of arthritis, this synovium often becomes inflamed and irritated, leading to synovitis. Arthrosamid Hydrogel injection aids in alleviating this inflammation by being absorbed by the synovial cells, which then become more dispersed, diminishing the transmission of inflammatory signals. Additionally, the hydrogel serves as a cushion within the knee joint. It typically takes approximately 6-8 weeks post-injection for Arthrosamid to integrate with the synovial cells and begin reducing knee joint pain, swelling, and increasing function.

The Procedure:

Before the injection, you’ll receive a single dose of antibiotics to mitigate the risk of infection. A pre-procedure ultrasound scan of the knee will be conducted to pinpoint the optimal site for the injection and assess any excess fluid in the joint. Following this, the skin will be meticulously cleaned and prepared using sterile techniques. A small amount of local anesthetic will be administered to numb the area. Subsequently, under continuous ultrasound guidance, the Arthrosamid hydrogel will be accurately injected into the knee joint. If there is any excess fluid present, it will be aspirated before the Arthrosamid injection.

It is important to follow your clinician post-procedure instructions carefully and attend follow the knee rehabilitation programme.


Step 1. Free Intial consultation

London Bridge Regenerative clinic gives every patient a free consultation with one of our injecting practitioners. There is no obligation to proceed to treatment. The consultation is an opportunity to discuss your issue in detail and the benefits and risks of the procedure. The advantages of Arthrosamid® is its its ability to provide joint cushioning, resulting in pain reduction, decreased stiffness, and improved mobility. Demonstrated to be safe, it offers long-lasting pain relief, ultimately enhancing your quality of life.


We will allow time to find out more about the procedure, understand the advantages and risks with the procedure, and to give time for you to ask questions We may need to refer you for an MRI We  will then take your medical history, examine which may include diagnostic ultrasound then proceed with the guided injection. 


You’ll be given individual pre-injection advice to reduce your chance of bleeding or infection and support your recovery and aid healing It’s important to let your practitioner know if you’re on any prescription or over-the-counter medications. You may be asked to stop taking aspirin or anti-inflammatory tablets, which can increase the risk of bruising. It’s also important to stop smoking cigarettes and e-cigarettes before and after the procedure because they can disrupt the healing process. Local aesthetic is normally needed as well is an antibiotic which must be taken 2 hours before the procedure 


Following the procedure, most individuals can return home and resume their normal activities. Our clinical team will be available to offer water and provide guidance on post-injection care. For the next twenty-four hours, it’s advisable to refrain from strenuous activities and alcohol consumption. Don’t be alarmed if you don’t notice immediate effects; it typically takes around five days for the injection to take effect, with the full results becoming evident over the course of several weeks. A follow-up appointment or phone consultation will be scheduled for 12 weeks after the course of treatment to review the progress. 



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